Chasteberry (Vitex agnus castus) has a long history of use in traditional herbal medicine.
Several clinical studies have concluded Vitex agnus castus ability to stimulate and stabilize hormones involved in ovulation, regularity and the extent menstrual blood loss.
Vitexin is not a hormone. It acts on the hypothalamus and pituitary glands which in turn secrete hormones or send signals to other parts of the body triggering the production of reproductive hormones. Vitexin increases luteinizing hormone production (LH) while reducing the secretion of follicle stimulating hormone (FSH). In effect, Vitexin stimulates the hormones involved in ovulation, helping to restore overall hormonal balance. More specific, Vitexin is effective in regulating pituitary gland leading to normalization of progesterone-estrogen balance. Normalization of progesterone and maintaining menstrual cycle regularity is required in order to avoid ovarian cysts formation caused by estrogen dominance.
Vitexin also has a positive effect on female fertility, several studies concluding that Vitex agnus castus increases fertility in women with significantly more multiple pregnancies compared with placebo.
Prolactin is designed to lock the two hormones necessary for ovulation: follicle stimulating hormone and gonadoliberin. When you have a very high level of prolactin in the blood (hyperprolactinemia), you will not ovulate, which means that you can not even get pregnant.
In a clinical trial (Milewicz, 1993), vitex was administered to patients with hyperprolactinemia. Vitex administration led to a decrease in prolactin and progesterone levels and normalization of ovulation luteal phase. In one of the most cited studies (Bergmann, 2000), 67 women suffering from infertility and ovulation problems were treated with Vitex. 38 women in the group became pregnant. Vitex is also recommended for women who are leaving the contraceptive pill, in which case Vitexin should be taken for a period of at least 3 menstrual cycles for cycle regulation and preparing for pregnancy.
The regulating the hormones, Vitexin is useful both in premenopause and menopause, a time in women’s life when the most acute hormonal imbalances occur.