ProteniX

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DESCRIPTION

What is ProteniX?

ProteniX™ contains an innovative combination of ingredients that provide chemical constituents important for health1 (Health Canada TCMI Monograph-2021).

Star anise (Illicium verum), is one of the vital ingredients of the Chinese medicinal herbs with the actions of dispelling cold and regulating the flow of Qi (vital energy). Several biologically important phytochemicals reported from Star Anise have shown to have antiviral effects and were studied against several viral pathogens. Star Anise is rich in Shikimic acid, a natural organic compound and one of the most widely studied molecules in the context of its antiviral effects 2 (Patra – 2020). Shikimic acid is also the intermediary model for the production of drugs effective against influenza viruses. Oseltamivir or Tamiflu derived from shikimic acid have been found to be potent influenza viral neuraminidase inhibitors against most influenza strains. When a virus penetrates a cell, it can also affect its DNA resulting in uncontrolled multiplication leading to cancer3 (Singh et al – 2020).

Star Anise extracts are also rich in phenolic antioxidants4 (Yang et al. -2012). Polyphenols promote immunity to foreign pathogens via various pathways due to the multiple types of polyphenol receptors on the immune cells which subsequently activate signaling pathways to initiate immune responses5 (Ding et al. – Regulation of Immune Function by Polyphenols, 2018).

Pinus sylvestris needle oil is an essential oil rich in monoterpene hydrocarbons (26.4–41.3%) and diterpenoids (6.2–13.7 %)6 (Judzentiene-2008). Scientists evaluated various terpenes for their anti-viral properties, among which monoterpenes showed good results. Diterpenoids (diterpenes) have antimicrobial properties because its ability to kill or stop the growth of microorganisms. Terpenes have a wide range of medicinal uses among which antiplasmodial (antimalarial) activity is notable as its mechanism of action is similar to the popular antimalarial drug—chloroquine7 (Cox-Georgian et al. -2019). The mechanism of action is the disruption of the protein complex that enables malaria-causing parasites to infect, replicate in red blood cells8 (Koning-Ward, Tania F. 2018). Some viruses also use proteins to penetrate cells. The ability to disrupt viral proteins can be of great value against certain types of viruses that use proteins to penetrate and infect the cell. The ability to disrupt abnormal proteins that are carcinogenic can be very important in the fight against malignancies.

Fenugreek (Trigonella foenum-graecum) is known in Traditional Chinese Medicine (TCM) as a “phlegm mover”. In TCM, Phlegm is one of the pathogenic factors (disease causing) responsible for the occurrence and development of a range of disorders. In translation, the internal mucus (Phlegm) is often formed by dysfunction of the lungs and the spleen caused by “internal fire”9 (CPh -2010). Spleen is an important element of the immune system. In TCM it is said that as “Fire” has an ascending property it will affect the upper regions of our body including lungs. For health matters, “Fire” may also be seen as having a fever.

The combination of these 3 ingredients creates a powerful synergistic and complementary formulation with a broad spectrum of action in respiratory infections.

Who should take it?

Preventative or as a treatment to improve the flow of vital energy through meridians, to balance yin-yang and expel pathogenic factors. In other words, to prevent or treat viral infection of the respiratory tract and to increase the body’s ability to fight against carcinogen agents.

COMPOSITION

What does ProteniX contain?

Ingredients / capsule:

50:1 aqueous extract of Anise-star fruit (Illicium verum) 228 mg
Pine (Pinus sylvestris) oily extract (dicalcium phosphate) 228 mg
Hydroethanolic extract from fenugreek seeds (Trigonella foenum-graecum) 225 mg
Capsule: hydroxypropylmethylcellulose
Charging agents: microcrystalline cellulose, potato starch
Antioxidant: ascorbyl palmitate
Anti-caking agent: magnesium salts of vegetable fatty acids

Does not contain: dyes, preservatives or artificial sweeteners, dairy products, wheat, gluten, ferments, soy, corn, eggs, nuts.

Net weight e = 49,02 g.

ADMINISTRATION

Recommended dose (adults): 1 capsule 1-2 times a day. Consult a specialist for long-term use.

Administer with:

Warnings and Precautions:

  • Do not use if you are pregnant or breast-feeding.
  • Discontinue use and consult your healthcare practitioner if any unpleasant symptoms persist or if you develop other symptoms.
  • Dietary supplements do not replace a varied and balanced diet and a healthy lifestyle

References

  1. Health Canada – Traditional Chinese Medicine Ingredients (TCMI) – 2021
  2. Jayanta Kumar Patra et al. – Star anise (Illicium verum): Chemical compounds, antiviral properties, and clinical relevance, Phytotherapy Research. 2020;1–20.
  3. Priyanka Singh et al. – Shikimic acid as intermediary model for the production of drugs effective against influenza virus – Phytochemicals as Lead Compounds for New Drug Discovery. Elsevier 2020 Chapter 16: 245–256
  4. Cheng-Hong Yang et al. – Investigation of the antioxidant activity of Illicium verum extracts- Journal of Medicinal Plants Research Vol. 6(2), pp. 314-324, 16 January 2012
  5. Sujuan Ding et al.- Journal of Immunology Research Volume 2018, Article ID 1264074
  6. Asta Judzentiene and Eugenija Kupcinskiene – Chemical Composition on Essential Oils from Needles of Pinus sylvestris L. Grown in Northern Lithuania-26/Journal of Essential Oil Research-Vol. 20, January/February 2008
  7. Destinney Cox-Georgian et al. – Therapeutic and Medicinal Uses of Terpenes- N. Joshee et al. (eds.), Medicinal Plants, Springer Nature Switzerland AG 2019; Chapter 15, page 333
  8. de Koning-Ward, Tania F. – Spotlight on proteins that aid malaria – Nature, Volume 561, Issue 7721, p.41-43 (2018)
  9. Pharmacopoeia of the Peoples Republic of China -2010

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*The results may vary from person to person, it is not mandatory to get the promised results mentioned on the site, or those already obtained by the persons who submitted their testimonials.