NADogen features

• Triple Action Formulation: Stimulates NAD+ synthesis through the de novo pathway, the Preiss–Handler pathway, and the salvage pathway.
• Key Ingredients: Incorporates Nicotinamide Riboside, Pterostilbene, and Tryptophan for maximum efficacy.
• Boost Cellular Energy: Specifically designed to amplify NAD+ levels, crucial for cellular energy metabolism.
• Combat Aging: Mitigates the metabolic decline associated with aging by maintaining high NAD+ levels.
• Safe & Sustainable: Uses antioxidant Pterostilbene to enhance Nicotinamide Riboside’s capacity to boost NAD+ and awaken the anti-aging gene.

NAD⁺ and aging are deeply connected — and it’s one of the most exciting areas in anti-aging research right now. Here’s the breakdown:

As we get older, NAD⁺ levels decline significantly — sometimes by more than 50% by middle age. This drop is linked to many age-related problems: 

• Mitochondrial dysfunction (less cellular energy)
• Increased DNA damage
• Chronic inflammation
• Decreased cellular repair capacity
• Neurodegeneration
• Metabolic decline 

NAD⁺ and the Longevity Pathways

The connection between NAD⁺ and longevity mostly comes through the activation of sirtuins, which are like cellular guardians that:

• Protect DNA
• Boost mitochondrial function
• Reduce inflammation
• Improve metabolic efficiency

How NAD+ works in the body

NAD⁺ (nicotinamide adenine dinucleotide) is a crucial coenzyme in your body that plays a central role in energy metabolism and cellular health. Here’s how it works:

Energy Production

• NAD⁺ is key to turning the food you eat into energy.
• In glycolysis (glucose breakdown) and the citric acid cycle (Krebs cycle), NAD⁺ picks up electrons (becomes NADH).
• NADH then donates these electrons to the electron transport chain in mitochondria, which generates ATP, the body’s energy currency.
• NAD⁺ ↔ NADH
• This cycling between NAD⁺ and NADH is essential for keeping energy flowing.

Enzyme Helper (Coenzyme)

• NAD⁺ acts as a coenzyme for hundreds of enzymes involved in metabolic reactions, particularly oxidation-reduction (redox) reactions.

DNA Repair and Longevity

NAD⁺ activates a family of proteins called sirtuins and PARPs:

• Sirtuins: Help with DNA repair, stress resistance, inflammation control, and influence aging.
• PARPs: Repair damaged DNA. Their overactivation (like during heavy oxidative stress) can drain NAD⁺

Cellular Signaling

NAD⁺ is also involved in cell signaling pathways, including those controlling:

• Circadian rhythms
• Immune responses
• Inflammation

Ingredients / vegetable capsule:

*NRV – nutritional reference value according to Reg. no. 1169/2011

Does not contain: artificial colors, preservatives or sweeteners, dairy products, wheat, gluten, yeast, corn, eggs, nuts.

Recommended way of use (adults): 2 capsules once daily or as directed by a healthcare practitioner. Do not exceed recommended dose for daily consumption. Suitable for vegetarians and vegans.

Warnings:

• Do not use this product if you are pregnant or breastfeeding.
• Some people may experience gastrointestinal upset and/or diarrhea.
• If you experience hypersensitivity such as an allergy, discontinue use.
• Dietary supplements are not a substitute for a varied and balanced diet and a healthy lifestyle.
• Keep out of the reach and sight of small children.
• Store at room temperature, in a dry place and away from heat sources.
• Sealed for your protection.
• Refuse product if cap seal is broken.

Provita Nutrition and Health Inc., Port Coquitlam, BC V3C 1S2, CANADA