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NADogen – 60 vegetarian capsules
- Complex formulation to Boost NAD+ Levels, Support Cellular Energy Metabolism & Combats Aging.
- Dietary supplement.
NADogen features
- Triple Action Formulation: Stimulates NAD+ synthesis through the de novo pathway, the Preiss–Handler pathway, and the salvage pathway.
- Key Ingredients: Incorporates Nicotinamide Riboside, Pterostilbene, and Tryptophan for maximum efficacy.
- Boost Cellular Energy: Specifically designed to amplify NAD+ levels, crucial for cellular energy metabolism.
- Combat Aging: Mitigates the metabolic decline associated with aging by maintaining high NAD+ levels.
- Safe & Sustainable: Uses antioxidant Pterostilbene to enhance Nicotinamide Riboside’s capacity to boost NAD+ and awaken the anti-aging gene.
NAD⁺ and aging are deeply connected — and it’s one of the most exciting areas in anti-aging research right now. Here’s the breakdown:
As we get older, NAD⁺ levels decline significantly — sometimes by more than 50% by middle age. This drop is linked to many age-related problems:
- Mitochondrial dysfunction (less cellular energy)
- Increased DNA damage
- Chronic inflammation
- Decreased cellular repair capacity
- Neurodegeneration
- Metabolic decline
NAD⁺ and the Longevity Pathways
The connection between NAD⁺ and longevity mostly comes through the activation of sirtuins, which are like cellular guardians that:
- Protect DNA
- Boost mitochondrial function
- Reduce inflammation
- Improve metabolic efficiency
How NAD+ works in the body
NAD⁺ (nicotinamide adenine dinucleotide) is a crucial coenzyme in your body that plays a central role in energy metabolism and cellular health. Here’s how it works:
Energy Production
- NAD⁺ is key to turning the food you eat into energy.
- In glycolysis (glucose breakdown) and the citric acid cycle (Krebs cycle), NAD⁺ picks up electrons (becomes NADH).
- NADH then donates these electrons to the electron transport chain in mitochondria, which generates ATP, the body’s energy currency.
- NAD⁺ ↔ NADH
- This cycling between NAD⁺ and NADH is essential for keeping energy flowing.
Enzyme Helper (Coenzyme)
- NAD⁺ acts as a coenzyme for hundreds of enzymes involved in metabolic reactions, particularly oxidation-reduction (redox) reactions.
DNA Repair and Longevity
NAD⁺ activates a family of proteins called sirtuins and PARPs:
- Sirtuins: Help with DNA repair, stress resistance, inflammation control, and influence aging.
- PARPs: Repair damaged DNA. Their overactivation (like during heavy oxidative stress) can drain NAD⁺
Cellular Signaling
NAD⁺ is also involved in cell signaling pathways, including those controlling:
- Circadian rhythms
- Immune responses
- Inflammation
Summary:
| Function | What NAD⁺ Does |
| Energy Metabolism | Transfers electrons, helps make ATP |
| Enzyme Activity | Works with enzymes in redox reactions |
| DNA Repair | Activates PARPs and sirtuins |
| Longevity & Aging | Supports cellular resilience |
| Immune & Cell Signals | Regulates key pathways |
